If secondary osteoporosis, bone loss caused by certain lifestyle behaviors, diseases and medications. Others, such as prednisone. Take: The loss of bone mass is a very common side effect of these drugs. In fact, the effect of glucocorticoids is 16-18% of osteoporosis in men. The damage these drugs cause may be due to their direct effect on bone, muscle weakness or real estate, reduced intestinal absorption of calcium, decreased testosterone levels and, most likely a combination of these factors. Bone mass is reduced, often quickly and continuously extended use of glucocorticoids, with most of bone loss in ribs and vertebrae. About a third of patients with signs of vertebral fractures after 5 to 10 years of treatment glucocorticoids. The risk of hip fracture increased almost three times. Thus, patients taking these drugs should talk to your doctor about bone mineral density (BMD) testing, men should also be tested to monitor testosterone levels, as glucocorticoids often reduce testosterone levels. Adequate calcium and vitamin D nutrition is important because these nutrients help reduce the impact of glucocorticoids on bone. Other possible treatments include testosterone replacement and medications. and two bisphosphonates drugs approved by FDA for use of men and women with osteoporosis caused by glucocorticoids. refers to abnormally low levels of sex hormones. It is well known that loss of estrogen causes osteoporosis in women. In men, lower levels of sex hormones may also lead to osteoporosis. In fact, an lasix 40 mg daily estimated 30% of men with osteoporosis vertebral fractures have low testosterone levels. Although it is only natural testosterone decreases with age, there should be a sharp drop in this hormone comparable to falling estrogen levels experienced by women during menopause. However, drugs like steroids, cancer treatment (especially prostate cancer), and many other factors can affect testosterone levels. Testosterone replacement therapy may be useful to prevent or slow bone loss. Its success depends on factors such as age and how much testosterone were reduced. In addition, it is not clear how long any positive effect of testosterone will continue, so doctors usually treat osteoporosis directly, by means of drugs approved for this purpose. Recent studies show that lack of estrogen can cause osteoporosis in men. For example, low estrogen levels in men with hypogonadism and may play a role in bone loss. Osteoporosis was found in some men who have rare disorders estrogen. Thus, the role of estrogen in men is under active investigation. There is plenty of evidence that alcohol abuse can decrease bone density and leads to an increase in fractures. Low bone mass is 25 to 50% of men who seek treatment for alcohol abuse. One of the first studies have shown bone mass of young alcoholic men be comparable to older women. In cases where bone loss is associated with alcohol abuse, the first goal of treatment is, of course, to help the patient stop - or at least reduce - his consumption of alcohol. Loss of bone mass faster and the pace of hip and vertebral fractures is higher among men who smoke, although more research is needed to determine how smoking damages bone. Tobacco, nicotine and other chemicals in cigarettes can be directly toxic to bone, or they may interfere with absorption of calcium and other nutrients necessary for healthy bones. Exodus is an ideal approach, of course, as smoking is harmful in many ways. Some nutrients, including amino acids, calcium, magnesium, phosphorus and vitamins D and K are important for bone health. Diseases of the stomach and intestines can lead to bone disease, if they impair absorption of nutrients. Treatment of osteoporosis in this case may include updating poorly absorbed nutrient (s). .
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